4-CPPC
Product Specifications
CAS Number
29553-70-6
Target
MIF, Others, CD74
Related Pathways
Immunology/Inflammation, Others
Purity
0.9803
Bioactivity
4-CPPC is an inhibitor of macrophage migration inhibitory factor-2 (MIF-2; IC50= 27 μM) .1It is selective for MIF-2 over MIF-1 (IC50= 450 μM) . It inhibits MIF-2, but not MIF-1, binding to CD74in vitrowhen used at a concentration of 10 μM. 4-CPPC (5, 10, and 25 μM) inhibits MIF-2-induced ERK1/2 phosphorylation in primary human skin fibroblasts.
Smiles
OC(=O)C1=CC=CC(=C1)C1=CC(=NC=C1C(O)=O)C(O)=O
Molecular Formula
C14H9NO6
Molecular Weight
287.22
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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