TH1217
Product Specifications
CAS Number
1862212-48-3
Target
Others, SARS-CoV
Related Pathways
Others, Microbiology/Virology
Purity
0.9964
Bioactivity
TH1217, a potent and selective inhibitor of dCTPase pyrophosphatase 1 (dCTPase), demonstrates an IC50 value of 47 nM. It amplifies the cytotoxic impact of cytidine analogues on leukemia cells and exhibits potential against COVID-19 by modulating SARS-CoV-2 interactors.
Smiles
Cc1nc2c(c(Cl)c(Cl)cc2n1Cc1ccc(cc1)[B-]12OC(=O)C[N+]1(C)CC(=O)O2)[N+]([O-])=O
Molecular Formula
C20H17BCl2N4O6
Molecular Weight
491.09
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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