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TH1217

Product Specifications

CAS Number

1862212-48-3

Target

Others|||SARS-CoV

Related Pathways

Others|||Microbiology/Virology

Purity

0.9964

Bioactivity

TH1217, a potent and selective inhibitor of dCTPase pyrophosphatase 1 (dCTPase), demonstrates an IC50 value of 47 nM. It amplifies the cytotoxic impact of cytidine analogues on leukemia cells and exhibits potential against COVID-19 by modulating SARS-CoV-2 interactors.

Smiles

Cc1nc2c(c(Cl)c(Cl)cc2n1Cc1ccc(cc1)[B-]12OC(=O)C[N+]1(C)CC(=O)O2)[N+]([O-])=O

Molecular Formula

C20H17BCl2N4O6

Molecular Weight

491.09

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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