Nirogacestat dihydrobromide

Product Specifications

CAS Number

1962925-29-6

Target

Apoptosis|||Gamma-secretase|||Others

Related Pathways

Apoptosis|||Proteases/Proteasome|||Others|||Neuroscience|||Stem Cells

Bioactivity

Potent ?-secretase inhibitor (IC50 values are 1.2 and 6.2 nM in whole cell and cell-free assays, respectively) . Reduces A? in brain, CSF and plasma in mice and guinea pigs.

Smiles

Br.Br.CCC[C@H](N[C@H]1CCc2cc(F)cc(F)c2C1)C(=O)Nc1cn(cn1)C(C)(C)CNCC(C)(C)C

Molecular Formula

C27H43Br2F2N5O

Molecular Weight

651.48

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

HY-RS23280 1 Set

Nek2 Rat Pre-designed siRNA Set A

Ask

View Details

MBS2009082-01 0.01 mg

Recombinant Tyrosine 3/Tryptophan 5 Monooxygenase Activation Protein Zeta (YWHAz)

Ask

View Details

MBS2009082-02 0.05 mg

Recombinant Tyrosine 3/Tryptophan 5 Monooxygenase Activation Protein Zeta (YWHAz)

Ask

View Details

MBS2009082-03 0.1 mg

Recombinant Tyrosine 3/Tryptophan 5 Monooxygenase Activation Protein Zeta (YWHAz)

Ask

View Details

MBS2009082-04 0.2 mg

Recombinant Tyrosine 3/Tryptophan 5 Monooxygenase Activation Protein Zeta (YWHAz)

Ask

View Details

MBS2009082-05 0.5 mg

Recombinant Tyrosine 3/Tryptophan 5 Monooxygenase Activation Protein Zeta (YWHAz)

Ask

View Details