Nirogacestat dihydrobromide

Product Specifications

CAS Number

1962925-29-6

Target

Apoptosis|||Gamma-secretase|||Others

Related Pathways

Apoptosis|||Proteases/Proteasome|||Others|||Neuroscience|||Stem Cells

Bioactivity

Potent ?-secretase inhibitor (IC50 values are 1.2 and 6.2 nM in whole cell and cell-free assays, respectively) . Reduces A? in brain, CSF and plasma in mice and guinea pigs.

Smiles

Br.Br.CCC[C@H](N[C@H]1CCc2cc(F)cc(F)c2C1)C(=O)Nc1cn(cn1)C(C)(C)CNCC(C)(C)C

Molecular Formula

C27H43Br2F2N5O

Molecular Weight

651.48

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

GTR15369860 1 Vial

Lentiviral human CNPY2 sgRNA gene knockout kit - Lentiviral human CNPY2 sgRNA gene knockout kit (plasmid)

Ask

View Details

NBP1-76568UV 0.1 mL

Rabbit Polyclonal PRR5L Antibody [DyLight 350]

Ask

View Details

A16254-100UG 100 µg

NFKB1 Antibody

Ask

View Details

bsm-62628R-PerCP-01 20 µL

MTAP Recombinant Antibody, PerCP Conjugated

Ask

View Details

bsm-62628R-PerCP-02 100 µL

MTAP Recombinant Antibody, PerCP Conjugated

Ask

View Details

132032-ML750 100 µL

PTGIS (Prostacyclin Synthase, Prostaglandin I2 Synthase, CYP8, CYP8A1, MGC126858, MGC126860) (MaxLight 750) discontinued

Ask

View Details