Sphingosine (d14:1)
Product Specifications
CAS Number
24558-60-9
Target
Others, PKC
Related Pathways
Cytoskeletal Signaling, Chromatin/Epigenetic, Others
Bioactivity
Sphingosine (d14:1) is a bioactive sphingolipid that has been found in B. mori (silkworm), P. clarkii (crayfish), and A. aurita (jellyfish) extracts. It increases the germination rate of N. rileyi, an entomopathogenic fungus, with an EC50 value of 10.2 nM. Sphingosine (d14:1) inhibits protein kinase C (PKC) in vitro (IC50 = 7.3 mol%) as well as superoxide generation induced by phorbol 12-myristate 13-acetate in neutrophils and reduces growth of CHO cells (IC50s = 19 and 8 μM, respectively) .
Smiles
C(\[C@H]([C@H](CO)N)O)=C/CCCCCCCCC
Molecular Formula
C14H29NO2
Molecular Weight
243.39
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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