L-Sepiapterin
Product Specifications
CAS Number
17094-01-8
Target
Others, Endogenous Metabolite
Related Pathways
Metabolism, Others
Bioactivity
L-Sepiapterin, also known as Sepiapterin, is a precursor compound crucial for the production of tetrahydrobiopterin (BH4), which serves as a coenzyme for endothelial nitric oxide synthase (eNOS) . This compound demonstrates its efficacy by improving endothelial dysfunction in small mesenteric arteries from db/db mice and promoting angiogenesis. Moreover, L-Sepiapterin exerts inhibitory effects on cellular proliferation and migration in ovarian cancer cells through the down-regulation of p70S6K-dependent vascular endothelial growth factor receptor-2 (VEGFR-2) expression[1][2].
Smiles
O=C1C2=C(NCC(C([C@H](C)O)=O)=N2)NC(N)=N1
Molecular Formula
C9H11N5O3
Molecular Weight
237.22
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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