Iromycin A
Product Specifications
CAS Number
213137-53-2
Target
Others, NO Synthase
Related Pathways
Immunology/Inflammation, Others
Bioactivity
Iromycin A is a bacterial pyridone metabolite that inhibits nitric oxide synthase (NOS) activity, with selectivity for NOS III (endothelial NOS) over NOS I (neuronal NOS) . Iromycin metabolites and derivatives block NADH oxidation in beef heart submitochondrial particles (IC50 = 0.461 μM for iromycin A) .
Smiles
C(/C=C(/C/C=C/C(C)C)\C)C1=C(CCC)C(O)=C(C)C(=O)N1
Molecular Formula
C19H29NO2
Molecular Weight
303.44
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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