R 121919 hydrochloride
Product Specifications
CAS Number
195055-66-4
Target
Others, CRFR
Related Pathways
GPCR/G Protein, Others
Bioactivity
High affinity corticotropin releasing factor receptor1 (CRF1) antagonist (Ki = 3.5 nM) . Reduces stress-induced elevations of plasma ACTH. Anxiolytic and antidepressant in vivo. Orally bioavailable.
Smiles
Cl.CCCN(CCC)c1cc(C)nc2c(c(C)nn12)-c1cnc(cc1C)N(C)C
Molecular Formula
C22H33ClN6
Molecular Weight
417
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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