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MPro N3

Product Specifications

CAS Number

884650-98-0

Target

SARS-CoV|||Others|||Virus Protease

Related Pathways

Microbiology/Virology|||Others

Bioactivity

Coronavirus main protease (Mpro) inhibitor (respective IC50 values are 2.7, 4 and 8.8 ?M for MHV-A29, HCoV-229E and FOPV replication in vitro) . Inhibits viral cell infection in an MHV plaque reduction assay. Also inhibits SARS-CoV-2 viral cell entry in a plaque reduction assay (IC50 = 16.8 ?M) .

Smiles

[C@@H](C[C@H]1C(=O)NCC1)(NC([C@@H](NC([C@@H](NC([C@@H](NC(=O)C=2C=C(C)ON2)C)=O)C(C)C)=O)CC(C)C)=O)/C=C/C(OCC3=CC=CC=C3)=O

Molecular Formula

C35H48N6O8

Molecular Weight

680.79

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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