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STING18

Product Specifications

CAS Number

2706536-26-5

Target

Others

Related Pathways

Others

Bioactivity

STING18 is a competitive ligand of stimulator of interferon genes (STING; IC50 = 0.068 μM in a radioligand binding assay) .1 It inhibits cGAMP-induced IFN-β production (IC50 = 11 μM) but does not stimulate IFN-β production (EC50 = >30 μM) in THP-1 cells.

Smiles

O=C(O)CC1C2=CC=C(F)C=C2C(=O)N(C3=CC=C(C(Cl)=C3)C(C)(C)C)C1C4=CC=C5OCCOC5=C4

Molecular Formula

C29H27ClFNO5

Molecular Weight

523.98

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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