Ricinelaidic Acid
Product Specifications
CAS Number
540-12-5
Target
Others|||Endogenous Metabolite|||Calcium Channel|||Leukotriene Receptor
Related Pathways
Metabolism|||GPCR/G Protein|||Others|||Membrane transporter/Ion channel
Bioactivity
Ricinelaidic acid is a 12-hydroxy fatty acid and an antagonist of leukotriene B4 (LTB4) receptors (Ki = 2 ?M in porcine neutrophil membranes) . It inhibits chemotaxis and calcium flux induced by LTB4 in isolated human neutrophils (IC50s = 10 and 7 ?M, respectively) . Ricinelaidic acid (1 mg/kg, i.v.) inhibits bronchoconstriction induced by LTB4 in rats by 46%.
Smiles
[C@H](C/C=C/CCCCCCCC(O)=O)(CCCCCC)O
Molecular Formula
C18H34O3
Molecular Weight
298.46
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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