5 (6) -Carboxy-2′,7′-dichlorofluorescein diacetate
Product Specifications
CAS Number
127770-45-0
Target
Others, Reactive Oxygen Species
Related Pathways
Metabolism, Others, NF-κB, Immunology/Inflammation
Bioactivity
5 (6) -Carboxy-2',7'-dichlorofluorescein diacetate is an oxidant-sensitive and cell-permeable fluorescent probe.1Base hydrolysis of the ester bonds by intracellular esterases releases the acetate groups and the resulting compound, 5 (6) -carboxy-2',7', -dichlorofluorescein, is oxidized by reactive oxygen species (ROS) and nitric oxide (NO) and displays excitation/emission maxima of 504 and 530 nm, respectively, which can be quantified as a measure of oxidant production.
Smiles
CC(=O)Oc1cc2Oc3cc(OC(C)=O)c(Cl)cc3C3(OC(=O)c4cc(ccc34)C(O)=O)c2cc1Cl.CC(=O)Oc1cc2Oc3cc(OC(C)=O)c(Cl)cc3C3(OC(=O)c4ccc(cc34)C(O)=O)c2cc1Cl
Molecular Formula
C25H14Cl2O9
Molecular Weight
529.3
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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