JC-171
Product Specifications
CAS Number
2112809-98-8
Target
NOD-like Receptor (NLR), Others
Related Pathways
Immunology/Inflammation, Others
Bioactivity
JC-171, a selective inhibitor of the NLRP3 inflammasome, effectively inhibits LPS/ATP-induced interleukin-1β (IL-1β) release from J774A.1 macrophages with an IC50 of 8.45 μM[1].
Smiles
COc1ccc(Cl)cc1C(=O)NCCc1ccc(cc1)S(=O)(=O)NO
Molecular Formula
C16H17ClN2O5S
Molecular Weight
384.83
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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