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(R) -KT109

Product Specifications

CAS Number

2055172-60-4

Target

Others

Related Pathways

Others

Bioactivity

(R) -KT109 is the (R) isomer of the diacylglycerol lipase β (DAGLβ) inhibitor KT109 . (R) -KT109 is an inhibitor of DAGLβ (IC50 = 0.79 nM) and of DAGLα-mediated hydrolysis of 1-stearoyl-2-arachidonoyl-sn-glycerol . It also inhibits α/β-hydrolase domain-containing protein 6 (ABHD6) with an IC50 value of 2.51 nM. (R) -KT109 is more potent at DAGLβ, DAGLα, and ABHD6 than (S) -KT109 .

Smiles

C(=O)(N1[C@@H](CC2=CC=CC=C2)CCCC1)N3C=C(N=N3)C4=CC=C(C=C4)C5=CC=CC=C5

Molecular Formula

C27H26N4O

Molecular Weight

422.52

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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