Herquline A
Product Specifications
CAS Number
71812-08-3
Target
Others, Influenza Virus
Related Pathways
Microbiology/Virology, Others
Bioactivity
Herquline A is an alkaloid fungal metabolite originally isolated from P. herquei. It inhibits cell death induced by influenza A strain A/PR/8/34 in MDCK cells with an IC50 value of 10 μg/ml and inhibits viral replication in a plaque assay in a concentration-dependent manner. Herquline A also inhibits platelet aggregation induced by ADP and platelet-activating factor (PAF) in vitro (IC50s = 180 and 240 μM, respectively) .
Smiles
[H][C@@]12C[C@@]3([H])CCC(=O)[C@@]4([H])[C@@]3([H])N1C[C@]([H])(CC1=C[C@@]4([H])C(=O)CC1)N(C)C2 |t:20|
Molecular Formula
C19H26N2O2
Molecular Weight
314.429
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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