P11149
Product Specifications
CAS Number
164724-79-2
Target
Cholinesterase (ChE), Others
Related Pathways
Others, Neuroscience
Bioactivity
P11149, a derivative of Galanthamine, acts as a competitive, orally active, and selective AChE inhibitor with the ability to weakly penetrate the blood-brain barrier (BBB) . It demonstrates selective inhibition, exhibiting an IC50 of 1.3 μM for rat BChE/AChE, and shows central cholinergic activity, behavioral efficacy, and safety. P11149 is utilized in Alzheimer's disease research[1].
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Cl.CN1CC[C@@]23C=C[C@H](O)C[C@@H]2Oc2c3c(C1)ccc2OC(=O)C12CC3CC(CC(C3)C1)C2
Molecular Formula
C27H34ClNO4
Molecular Weight
472.02
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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