ML-309 (hydrochloride)
Product Specifications
CAS Number
1355327-02-4
Target
Others
Related Pathways
Others
Bioactivity
ML-309 is an inhibitor of mutant isocitrate dehydrogenase 1 (IDH1) . It reversibly and selective inhibits IDH1R132H over wild-type IDH1 (IC50s = 96 and 36,500 nM, respectively) . ML-309 reduces 2-hydroxyglutarate production in U87 MG glioblastoma cells (EC50 = 55 nM) .
Smiles
Cl.Cc1ccccc1C(N(C(=O)Cn1cnc2ccccc12)c1cccc(F)c1)C(=O)NC1CCCC1
Molecular Formula
C29H30ClFN4O2
Molecular Weight
521.03
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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