DL 175
Product Specifications
CAS Number
2487253-25-6
Target
Others
Related Pathways
Others
Bioactivity
Potent and selective GPR84 biased agonist (EC50 = 33 nM) . Exhibits no significant activity in a panel of 168 other GPCRs. Exhibits bias for G protein signaling pathways. Induces morphological changes in primary murine bone marrow-derived macrophages (BMDMs) in a cellular impedance assay, and promotes phagocytosis by M1 polarized U937 cells. Induces migration of primary human monocytes, but has no effect on macrophage chemotaxis.
Molecular Formula
C17H14ClNO2
Molecular Weight
299.75
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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