PM226
Product Specifications
CAS Number
1949726-13-9
Target
Others, Cannabinoid Receptor
Related Pathways
Others, GPCR/G Protein
Bioactivity
Potent and selective CB2 receptor agonist (Ki = 12.8 nM; EC50 = 38.67 nM) . Exhibits negligible affinity for the CB1 receptor (Ki > 40,000 nM) and no activity at the GPR55. Suppresses neuroinflammation by reducing microglial activation in a multiple sclerosis mouse model. BBB permeable; anti-inflammatory and neuroprotective.
Smiles
O(C)C1=C2C3=C(C(C)(C)OC2=CC(C(CCCCCC)(C)C)=C1)C=NO3
Molecular Formula
C22H31NO3
Molecular Weight
357.49
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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