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JNJ-55308942

Product Specifications

CAS Number

2166558-11-6

Target

P2X Receptor

Related Pathways

Neuroscience, Membrane transporter/Ion channel

Purity

>99.99%

Bioactivity

JNJ-55308942 is a selective and brain-penetrant antagonist of P2X7 functional with IC50s of 10 and 15 nM and Kis of 7.1 and 2.9 nM for hP2X7 and rP2X7, respectively.

Smiles

C[C@H]1Cc2c(CN1C(=O)c1ccnc(c1F)C(F)(F)F)nnn2-c1ncc(F)cn1

Molecular Formula

C17H12F5N7O

Molecular Weight

425.32

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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