PF 04671536 hydrochloride
Product Specifications
CAS Number
1305116-67-9
Target
Others|||PDE
Related Pathways
Metabolism|||Others
Bioactivity
Potent and selective PDE8B/8A inhibitor (IC50 values are 1.3 and 1.9 nM, respectively) . Exhibits selectivity for PDE8A/B over other PDEs (IC50 values are >10 ?M) and a range of other targets. Increases glucose-dependent insulin secretion from human pacreatic islet cells. Orally bioavailable.
Smiles
Cl.Cc1nc(N)c2nnn(C[C@H]3CN(Cc4nccs4)CCO3)c2n1
Molecular Formula
C14H19ClN8OS
Molecular Weight
382.87
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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