Thielavin A
Product Specifications
CAS Number
71950-66-8
Target
Prostaglandin Receptor|||Others
Related Pathways
Others|||GPCR/G Protein|||Immunology/Inflammation
Bioactivity
Thielavin A is a fungal metabolite originally isolated from T. terricola that is related to thielavin B . Thielavin A inhibits COX, blocking both the conversion of arachidonic acid to prostaglandin H2 and the conversion of PGH2 to PGE2 . Thielavin A also inhibits glucose-6-phosphatase in rat liver microsomes (IC50 = 4.6 ?M) . It is a non-competitive inhibitor of ?-glucosidase from S. cerevisiae (IC50 = 23.8 ?M; Ki = 27.8 ?M) .
Smiles
Cc1cc(O)c(C)c(O)c1C(=O)Oc1c(C)c(C)c(C(=O)Oc2c(C)c(C)c(C(O)=O)c(O)c2C)c(O)c1C
Molecular Formula
C29H30O10
Molecular Weight
538.549
Shipping Conditions
Cool pack
Storage Temperature
-20°C
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