ARN14974
ARN14974, a benzoxazolone carboxamide, is a potent and systemically active inhibitors of intracellular acid ceramidase (IC50=79 nM) [1].
Product Specifications
CAS Number
1644158-57-5
UNSPSC
12352005
Target
Ceramidase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/arn14974.html
Purity
99.29
Solubility
DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(N1C(OC2=CC(C3=CC=C(F)C=C3)=CC=C12)=O)NCCCCC4=CC=CC=C4
Molecular Formula
C24H21FN2O3
Molecular Weight
404.43
References & Citations
[1]Pizzirani D, et al. Benzoxazolone carboxamides: potent and systemically active inhibitors of intracellular acid ceramidase. Angew Chem Int Ed Engl. 2015;54 (2) :485-489.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
HP230876 200 Reactions
ELAPOR2 Human qPCR Primer Pair (NM_001142749)
Sign In for Pricing
View Details 
TRC-B600452-25MG 25 mg
N-(N-tert-Boc-alanoyl)-L-(2S,3aS,7aS)-octahydro-indole-2-carboxylic Acid-d4 Benzyl Ester
Sign In for Pricing
View Details 
