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Taurohyodeoxycholic acid

Product Specifications

CAS Number

2958-04-5

Target

Interleukin, Endogenous Metabolite, Glutathione Peroxidase, Cytochromes P450, IL Receptor, COX, TNF

Related Pathways

Neuroscience, Apoptosis, Immunology/Inflammation, Metabolism

Purity

0.9938

Bioactivity

Taurohyodeoxycholic acid (THDCA) is a bile acid that plays a key role in regulating the hepatic inflammatory microenvironment.THDCA reduces the expression of TNF-α and IL-6 and inhibits the development of hepatocellular carcinoma (HCC) . It is able to inhibit non-alcoholic fatty liver disease and regulate bile acid metabolism in combination with astragalus polysaccharides: it reduces CD36 expression in the liver and decreases hepatic lipid accumulation by up-regulating CYP7B1 and down-regulating CYP7A1.

Smiles

C[C@@]12[C@@]3([C@]([C@]4([C@](C)(CC3)[C@@]([C@@H](CCC(NCCS(=O)(=O)O)=O)C)(CC4)[H])[H])(C[C@H](O)[C@@]1(C[C@H](O)CC2)[H])[H])[H]

Molecular Formula

C26H45NO6S

Molecular Weight

499.7

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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