Taurohyodeoxycholic acid
Product Specifications
CAS Number
2958-04-5
Target
Interleukin, Endogenous Metabolite, Glutathione Peroxidase, Cytochromes P450, IL Receptor, COX, TNF
Related Pathways
Neuroscience, Apoptosis, Immunology/Inflammation, Metabolism
Purity
0.9938
Bioactivity
Taurohyodeoxycholic acid (THDCA) is a bile acid that plays a key role in regulating the hepatic inflammatory microenvironment.THDCA reduces the expression of TNF-α and IL-6 and inhibits the development of hepatocellular carcinoma (HCC) . It is able to inhibit non-alcoholic fatty liver disease and regulate bile acid metabolism in combination with astragalus polysaccharides: it reduces CD36 expression in the liver and decreases hepatic lipid accumulation by up-regulating CYP7B1 and down-regulating CYP7A1.
Smiles
C[C@@]12[C@@]3([C@]([C@]4([C@](C)(CC3)[C@@]([C@@H](CCC(NCCS(=O)(=O)O)=O)C)(CC4)[H])[H])(C[C@H](O)[C@@]1(C[C@H](O)CC2)[H])[H])[H]
Molecular Formula
C26H45NO6S
Molecular Weight
499.7
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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