Taurohyodeoxycholic acid
Product Specifications
CAS Number
386523
Target
Interleukin|||Endogenous Metabolite|||Glutathione Peroxidase|||Cytochromes P450|||IL Receptor|||COX|||TNF
Related Pathways
Neuroscience|||Apoptosis|||Immunology/Inflammation|||Metabolism
Purity
0.9938
Bioactivity
Taurohyodeoxycholic acid (THDCA) is a bile acid that plays a key role in regulating the hepatic inflammatory microenvironment.THDCA reduces the expression of TNF-? and IL-6 and inhibits the development of hepatocellular carcinoma (HCC) . It is able to inhibit non-alcoholic fatty liver disease and regulate bile acid metabolism in combination with astragalus polysaccharides: it reduces CD36 expression in the liver and decreases hepatic lipid accumulation by up-regulating CYP7B1 and down-regulating CYP7A1.
Smiles
C[C@@]12[C@@]3([C@]([C@]4([C@](C)(CC3)[C@@]([C@@H](CCC(NCCS(=O)(=O)O)=O)C)(CC4)[H])[H])(C[C@H](O)[C@@]1(C[C@H](O)CC2)[H])[H])[H]
Molecular Formula
C26H45NO6S
Molecular Weight
499.7
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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