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Rhapontigenin

Product Specifications

CAS Number

500-65-2

Target

Antibacterial, Cytochromes P450, Antifungal

Related Pathways

Microbiology/Virology, Metabolism

Purity

0.9988

Bioactivity

Rhapontigenin (Protigenin) is a mechanism-based, selective inactivator of cytochrome P450 1A1 (IC50: 400 nM), an aryl hydrocarbon hydroxylase which activates polycyclic aromatic hydrocarbons that act as procarcinogens. Rhapontigenin is a natural analog of resveratrol with antioxidant and anti-cancer activity. At higher concentrations, rhapontigenin inhibits the proliferation of HL-60R and HepG2 cancer cell lines (IC50: 48 μM) .

Smiles

COc1ccc(\C=C\c2cc(O)cc(O)c2)cc1O

Molecular Formula

C15H14O4

Molecular Weight

258.27

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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