Rhapontigenin
Product Specifications
CAS Number
500-65-2
Target
Antibacterial, Cytochromes P450, Antifungal
Related Pathways
Microbiology/Virology, Metabolism
Purity
0.9988
Bioactivity
Rhapontigenin (Protigenin) is a mechanism-based, selective inactivator of cytochrome P450 1A1 (IC50: 400 nM), an aryl hydrocarbon hydroxylase which activates polycyclic aromatic hydrocarbons that act as procarcinogens. Rhapontigenin is a natural analog of resveratrol with antioxidant and anti-cancer activity. At higher concentrations, rhapontigenin inhibits the proliferation of HL-60R and HepG2 cancer cell lines (IC50: 48 μM) .
Smiles
COc1ccc(\C=C\c2cc(O)cc(O)c2)cc1O
Molecular Formula
C15H14O4
Molecular Weight
258.27
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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