Org 24598
Product Specifications
CAS Number
372198-97-5
Target
Others|||GlyT
Related Pathways
Neuroscience|||Others
Bioactivity
Potent and selective inhibitor of the glial glycine transporter GlyT1b (IC50 = 6.9 nM) . Displays negligible activity at GlyT-2, adrenoreceptors, dopamine, 5HT receptors and noradrenaline, dopamine, 5HT and GABA transporters (pIC50 in vivo.
Smiles
[C@@H](OC1=CC=C(C(F)(F)F)C=C1)(CCN(CC(O)=O)C)C2=CC=CC=C2
Molecular Formula
C19H20F3NO3
Molecular Weight
367.36
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Curated Selection
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