5 (S) -HETE lactone
Product Specifications
CAS Number
127708-42-3
Target
Others, Drug Metabolite
Related Pathways
Others, Metabolism
Bioactivity
5 (S) -HETE lactone is a cyclic ester formed by acid-catalyzed nucleophilic addition of the C-5 hydroxyl to the C-1 carboxyl of 5 (S) -HETE. The ability of (±) 5-HETE lactone to inhibit rat basophilic leukemia cell 5-lipoxygenase (IC50 = 27 μM) may be entirely due to the 5 (S) isomer, but the enantiomers have not been tested separately.
Smiles
C(=C/C=C\C/C=C\C/C=C\CCCCC)\[C@H]1OC(=O)CCC1
Molecular Formula
C20H30O2
Molecular Weight
302.45
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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