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5 (S) -HETE lactone

Product Specifications

CAS Number

127708-42-3

Target

Others, Drug Metabolite

Related Pathways

Others, Metabolism

Bioactivity

5 (S) -HETE lactone is a cyclic ester formed by acid-catalyzed nucleophilic addition of the C-5 hydroxyl to the C-1 carboxyl of 5 (S) -HETE. The ability of (±) 5-HETE lactone to inhibit rat basophilic leukemia cell 5-lipoxygenase (IC50 = 27 μM) may be entirely due to the 5 (S) isomer, but the enantiomers have not been tested separately.

Smiles

C(=C/C=C\C/C=C\C/C=C\CCCCC)\[C@H]1OC(=O)CCC1

Molecular Formula

C20H30O2

Molecular Weight

302.45

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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