RANKL/TNFSF11, Human (HEK293, mFc)
RANKL (TNFSF11), a type II transmembrane protein, is a receptor activator of NF-κB (RANK) ligand. RANKL is an activator of RANK. When binding to RANK, it induces the differentiation of monocyte/macrophage-lineage cells into osteoclasts and leads to osteoclast precursor maturation. RANKL is critical for osteoclasts maturation, bone modeling, and bone remodeling, as well as the development of lymph nodes (LNs) . RANKL/TNFSF11 Protein, Human (HEK293, mFc) is a recombinant human RANKL (G63-D244) with N-terminal mFc tag, which is produced in HEK293 cell[1][2].
Product Specifications
Product Name Alternative
RANKL/TNFSF11 Protein, Human (HEK293, mFc), Human, HEK293
UNSPSC
12352202
Type
Recombinant Proteins
Assay Protocol
https://www.medchemexpress.com/cytokines/rank-l-tnfsf11-protein-human-hek293-fc.html
Purity
97.20
Molecular Formula
8600 (Gene_ID) O14788-2 (G63-D244) (Accession)
Molecular Weight
Approximately 50-65 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.
References & Citations
Shipping Conditions
Room temperature in continental US; may vary elsewhere.
Storage Conditions
Stored at -20°C for 2 years
Scientific Category
Recombinant Proteins
Available Sizes
Frequently Asked Questions
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