D-DOPA

Product Specifications

CAS Number

5796-17-8

Target

Carboxypeptidase|||Others

Related Pathways

Proteases/Proteasome|||Others

Bioactivity

D-DOPA is an enantiomer of the dopamine precursor L-DOPA . It can be converted to L-DOPAviasequential oxidation and transamination, which are mediated by D-amino acid oxidase (DAAO) and DOPA transaminase, respectively, in rat kidney homogenates.1It reduces the number of dopaminergic neurons in primary rat embryonic mesencephalic cultures in a concentration-dependent manner.2Intraventricular administration of D-DOPA (200 ?g/animal) increases striatal dopamine levels in rats.3D-DOPA (20 mg/kg, i.p.) induces contralateral turns in a rat model of Parkinson's disease induced by 6-OHDA .4

Smiles

N[C@H](Cc1ccc(O)c(O)c1)C(O)=O

Molecular Formula

C9H11NO4

Molecular Weight

197.19

Shipping Conditions

Cool pack

Storage Temperature

-20°C