Pericosine A
Product Specifications
CAS Number
200335-68-8
Target
Topoisomerase|||Others
Related Pathways
Others|||DNA Damage/DNA Repair
Bioactivity
Pericosine A is a fungal metabolite that has been found inP. byssoidesand has anticancer activity.1It inhibits the growth of a variety of cancer cells, including breast, colon, lung, ovary, stomach, and prostate cell lines (GI50s = 0.05-24.55 ?M) and increases survival in a P388 mouse xenograft model when administered at a dose of 25 mg/kg. Pericosine A inhibits EGFR by 40 to 70% when used at a concentration of 100 ?g/ml. It also reacts with organosulfur compounds in skunk spray to form stable thioethers as odorless products.2
Smiles
COC(=O)C1=C[C@H](O)[C@H](O)[C@H](O)[C@H]1Cl|t:4|
Molecular Formula
C8H11ClO5
Molecular Weight
222.62
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
