4-Isocyanato-TEMPO, Technical grade
4-isocyanato TEMPO is a spin labeling reagent used to label the 2’-position in RNA. It has been used to study HIV-1 transactivation response RNA and hammerhead ribosome dynamics by electron paramagnetic resonance (EPR) spectroscopy.
Product Specifications
CAS Number
88418-69-3
UNSPSC
12352005
Target
HIV
Type
Reference compound
Related Pathways
Anti-infection
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/4-isocyanato-tempo-technical-grade.html
Smiles
[O]N1C(C)(C)CC(N=C=O)CC1(C)C
Molecular Formula
C10H17N2O2
Molecular Weight
197.25
References & Citations
[1]Edwards, et al. Site-specific incorporation of nitroxide spin-labels into internal sites of the TAR RNA; structure-dependent dynamics of RNA by EPR spectroscopy. J. Am. Chem. Soc. 123 (7), 1527-1528 (2001) .
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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