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4-Isocyanato-TEMPO, Technical grade

4-isocyanato TEMPO is a spin labeling reagent used to label the 2’-position in RNA. It has been used to study HIV-1 transactivation response RNA and hammerhead ribosome dynamics by electron paramagnetic resonance (EPR) spectroscopy.

Product Specifications

CAS Number

88418-69-3

UNSPSC

12352005

Target

HIV

Type

Reference compound

Related Pathways

Anti-infection

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/4-isocyanato-tempo-technical-grade.html

Smiles

[O]N1C(C)(C)CC(N=C=O)CC1(C)C

Molecular Formula

C10H17N2O2

Molecular Weight

197.25

References & Citations

[1]Edwards, et al. Site-specific incorporation of nitroxide spin-labels into internal sites of the TAR RNA; structure-dependent dynamics of RNA by EPR spectroscopy. J. Am. Chem. Soc. 123 (7), 1527-1528 (2001) .

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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