ML 209
Product Specifications
CAS Number
1334526-14-5
Target
ROR
Related Pathways
Metabolism
Purity
0.9987
Bioactivity
ML-209 is an antagonist of retinoic acid receptor-related orphan receptor γt (RORγt; IC50= 1.1 μM in a reporter assay) .1It inhibits RORγt-induced transcription in HEK293T cells expressing the human receptor (IC50= 300 nM) . ML-209 inhibits RORγt-dependent differentiation of isolated na?ve cord blood human CD4+T cells into Th17 T helper cells.
Smiles
C(CC(=O)N1C[C@@H](C)C[C@@H](C)C1)(C2=C(OC)C=C(OC)C=C2O)C=3C=C4C(=CC3)OCO4
Molecular Formula
C25H31NO6
Molecular Weight
441.52
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
orb1579315 100 µL
Phospho-eNOS (Thr495) Rabbit Polyclonal Antibody (BF488)
Sign In for Pricing
View Details 
043644-ML550 100 µL
URB2, CT (URB2, KIAA0133, Unhealthy ribosome biogenesis protein 2 homolog) (MaxLight 550) discontinued
Sign In for Pricing
View Details 
130978-HRP 100 µL
PCDHGA8 (KIAA0327, Protocadherin gamma-A8, PCDH-gamma-A8) (HRP)
Sign In for Pricing
View Details