Tryptoquivaline D
Product Specifications
CAS Number
60676-56-4
Target
Others
Related Pathways
Others
Bioactivity
Tryptoquivaline D is a fungal metabolite found in [Neosartorya siamensis] with noted anticancer activity. It induces nuclear chromatin condensation, a marker of apoptosis, in HCT116 colon and HepG2 liver cancer cells at a concentration of 150 ?M. Tryptoquivaline D (1-100 ?M), alone or with doxorubicin, reduces the viability of A549 lung cancer cells.
Smiles
CC(C)[C@@H](OC(C)=O)c1nc2ccccc2c(=O)n1[C@H]1C[C@]2(OC1=O)[C@H]1N(O)[C@H](C)C(=O)N1c1ccccc21
Molecular Formula
C28H28N4O7
Molecular Weight
532.553
Shipping Conditions
Cool pack
Storage Temperature
-20°C
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