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Tryptoquivaline D

Product Specifications

CAS Number

60676-56-4

Target

Others

Related Pathways

Others

Bioactivity

Tryptoquivaline D is a fungal metabolite found in [Neosartorya siamensis] with noted anticancer activity. It induces nuclear chromatin condensation, a marker of apoptosis, in HCT116 colon and HepG2 liver cancer cells at a concentration of 150 ?M. Tryptoquivaline D (1-100 ?M), alone or with doxorubicin, reduces the viability of A549 lung cancer cells.

Smiles

CC(C)[C@@H](OC(C)=O)c1nc2ccccc2c(=O)n1[C@H]1C[C@]2(OC1=O)[C@H]1N(O)[C@H](C)C(=O)N1c1ccccc21

Molecular Formula

C28H28N4O7

Molecular Weight

532.553

Shipping Conditions

Cool pack

Storage Temperature

-20°C

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