Amycolatopsin B

Product Specifications

CAS Number

2209112-97-8

Target

Others, Antifungal

Related Pathways

Microbiology/Virology, Others

Bioactivity

Amycolatopsin B is a bacterial metabolite originally isolated fromAmycolatopsisthat has anticancer activity.1It is cytotoxic to NCI H460 lung and SW620 colon cancer cells (IC50s = 0.28 and 0.14 μM, respectively) .

Smiles

COCCC[C@H]1O[C@@](O)([C@H](C)C2CC(OC)C(O)\C=C(/C)\C=C(/C)\C=C(C)/C(O[C@H]3O[C@H](C)[C@@H](OC)[C@H](O)[C@H]3O)C(C)\C=C(/C)\C=C(\OC)/C=C(C)/C(=O)O2)[C@H](OC)[C@@H](O)[C@]1(C)O[C@H]1C[C@H](O)[C@H](O[C@H]2C[C@@](C)(O)[C@H](O)[C@@H](C)O2)[C@@H](C)O1 |c:18,21,43,50,t:24,46|