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L-858,051 (hydrochloride)

Product Specifications

CAS Number

115116-37-5

Target

Others

Related Pathways

Others

Bioactivity

L-858,051 is a water-soluble analog of forskolin , a cell-permeant activator of adenylate cyclase. L-858,051 activates adenylate cyclase (EC50 = 3 μM), inhibits glucose transport, and blocks cytochalasin B binding in rat adipocyte membranes. L-858,051 is used to activate adenylate cyclase and initiate signaling through elevated cAMP synthesis in a variety of cell types in culture.

Smiles

Cl.Cl.[H][C@@]12[C@H](O)[C@H](OC(=O)CCCN3CCN(C)CC3)[C@@]3(C)O[C@](C)(CC(=O)[C@]3(O)[C@@]1(C)[C@@H](O)CCC2(C)C)C=C

Molecular Formula

C29H50Cl2N2O7

Molecular Weight

609.63

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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