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CAY10704

Product Specifications

CAS Number

101784-44-5

Target

Others|||HCV Protease

Related Pathways

Microbiology/Virology|||Proteases/Proteasome|||Others

Bioactivity

CAY10704 is a potent inhibitor of hepatitis C virus (HCV) infection (EC50 = 17 nM) that displays low cytotoxicity of virally-infected human hepatoma Huh7.5.1 cells (CC50 = 21.3 ?M) . It displays good pharmacokinetics in mice when delivered intraperitoneally, with preferential liver distribution without significant hepatotoxicity. CAY10704 is selective for HCV over dengue virus (EC50 = 4.62 ?M) .

Smiles

C(C1=CC=C(Cl)C=C1)(C2=CC=C(Cl)C=C2)N3CCN(C)CC3

Molecular Formula

C18H20Cl2N2

Molecular Weight

335.27

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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