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CAY10781

Product Specifications

CAS Number

1210360-87-4

Target

Others, VEGFR

Related Pathways

Angiogenesis, Others, Tyrosine Kinase/Adaptors

Purity

0.9949

Bioactivity

CAY10781 is an inhibitor of the protein-protein interaction between neuropilin-1 (NRP-1) and VEGF-A.1It inhibits the interaction by 43% when used at a concentration of 12.5 μM. CAY10781 also inhibits VEGF-A-induced phosphorylation of VEGFR2 in catecholamine A-differentiated (CAD) cells when used at the same concentration.

Smiles

OC(=O)CC1=CNC(=NC1=O)C1=CN=CC=C1

Molecular Formula

C11H9N3O3

Molecular Weight

231.21

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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