CAY10781
Product Specifications
CAS Number
1210360-87-4
Target
Others|||VEGFR
Related Pathways
Angiogenesis|||Others|||Tyrosine Kinase/Adaptors
Purity
0.9949
Bioactivity
CAY10781 is an inhibitor of the protein-protein interaction between neuropilin-1 (NRP-1) and VEGF-A.1It inhibits the interaction by 43% when used at a concentration of 12.5 ?M. CAY10781 also inhibits VEGF-A-induced phosphorylation of VEGFR2 in catecholamine A-differentiated (CAD) cells when used at the same concentration.
Smiles
OC(=O)CC1=CNC(=NC1=O)C1=CN=CC=C1
Molecular Formula
C11H9N3O3
Molecular Weight
231.21
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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