Zetomipzomib
Product Specifications
CAS Number
1629677-75-3
Target
Proteasome, Others
Related Pathways
Proteases/Proteasome, Ubiquitination, Others
Bioactivity
KZR-616, a first-in-class inhibitor of the immunoproteasome, selectively targets the LMP7 (IC50: 39/57 nM=hLMP7/mLMP7) and LMP2 (IC50: 131/179 nM=hLMP7/mLMP7) subunits of the immunoproteasome. KZR-616 has the potential for the research of multiple autoimmune diseases[1][2].
Smiles
C([C@H](CC=1CCCC1)NC([C@H]([C@H](O)C2=CC=C(OC)C=C2)NC([C@@H](NC(CN3CCOCC3)=O)C)=O)=O)(=O)[C@@]4(C)CO4
Molecular Formula
C30H42N4O8
Molecular Weight
586.68
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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