Z-LLE-AMC
Product Specifications
CAS Number
348086-66-8
Target
Proteasome
Related Pathways
Ubiquitination, Proteases/Proteasome
Bioactivity
Z-LLE-AMC is a fluorogenic substrate for the caspase-like post-glutamate peptide hydrolase of the 26S proteasome or 20S proteolytic core. Caspase-like activity can be quantified by fluorescent detection of free AMC (also known as 7-amino-4-methylcoumarin), which is excited at 340-360 nm and emits at 440-460 nm. Z-LLE-AMC is typically used in cell lysates after experimental treatment.
Smiles
CC(C)C[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)Nc1ccc2c(C)cc(=O)oc2c1
Molecular Formula
C35H44N4O9
Molecular Weight
664.756
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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