TAN-67 (dihydrobromide)
Product Specifications
UNSPSC Description
TAN-67 (SB-205607) dihydrobromide is a potent and selective nonpeptidic δ-opioid receptor agonist with a Ki value of 0.647 nM. TAN-67 dihydrobromide has neuroprotective effect. TAN-67 dihydrobromide can be used in research of ischemic stroke[1][2].
Target Antigen
Opioid Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein;Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/tan-67-dihydrobromide.html
Purity
99.0
Solubility
10 mM in DMSO
Smiles
OC1=CC=CC([C@]23[C@@](CN(C)CC3)([H])CC4=CC5=CC=CC=C5N=C4C2)=C1.Br.Br
Molecular Weight
506.27
References & Citations
[1]Knapp RJ, et, al. Properties of TAN-67, a nonpeptidic delta-opioid receptor agonist, at cloned human delta- and mu-opioid receptors. Eur J Pharmacol. 1995 Oct 15;291(2):129-34.|[2]Min JW, et, al. The non-peptidic δ-opioid receptor agonist Tan-67 mediates neuroprotection post-ischemically and is associated with altered amyloid precursor protein expression, maturation and processing in mice. J Neurochem. 2018 Feb;144(3):336-347.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-101317/TAN-67-dihydrobromide-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-101317/TAN-67-dihydrobromide-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
1217628-73-3
Available Sizes
Curated Selection
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