GI-530159
Product Specifications
CAS Number
69563-88-8
Target
Others|||Potassium Channel
Related Pathways
Membrane transporter/Ion channel|||Others
Bioactivity
TREK1 and TREK2 channel activator (EC50 = 0.76 ?M in Rb efflux assay in TREK1-expressing CHO cells) . Exhibits selectivity for TREK1/2 over TRAAK, TASK3 and a range of other potassium channels. Hyperpolarizes membrane potential of dorsal root ganglion neurons and depresses neuronal activity in vitro.
Smiles
Nc1ccc(Oc2ccc(cc2)C(c2ccc(Oc3ccc(N)cc3)cc2)(C(F)(F)F)C(F)(F)F)cc1
Molecular Formula
C27H20F6N2O2
Molecular Weight
518.45
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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