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GI-530159

Product Specifications

CAS Number

69563-88-8

Target

Others, Potassium Channel

Related Pathways

Membrane transporter/Ion channel, Others

Bioactivity

TREK1 and TREK2 channel activator (EC50 = 0.76 μM in Rb efflux assay in TREK1-expressing CHO cells) . Exhibits selectivity for TREK1/2 over TRAAK, TASK3 and a range of other potassium channels. Hyperpolarizes membrane potential of dorsal root ganglion neurons and depresses neuronal activity in vitro.

Smiles

Nc1ccc(Oc2ccc(cc2)C(c2ccc(Oc3ccc(N)cc3)cc2)(C(F)(F)F)C(F)(F)F)cc1

Molecular Formula

C27H20F6N2O2

Molecular Weight

518.45

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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