JMJD6-IN-1
JMJD6-IN-1 (Compound 1-3) is a JMJD6 inhibitor, with an inhibition rate of 82% at 10 μM. JMJD6-IN-1 inhibits MCF-7 and HCC4006 cell proliferation with IC50s of 19.2 μM and 25.2 μM. JMJD6-IN-1 can be used for research of cancers[1].
Product Specifications
CAS Number
[899548-78-8]
UNSPSC
12352005
Hazard Statement
H315, H319
Target
Histone Demethylase
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/jmjd6-in-1.html
Purity
99.69
Solubility
DMF : 10 mg/mL (ultrasonic) |DMSO : 5 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C1C(C(N2)=NC3=C2C=NC=C3)=CC4=CC(C)=CC=C4O1
Molecular Formula
C16H11N3O2
Molecular Weight
277.28
Precautions
H315, H319
References & Citations
[1]Liu Wen, et al. Benzopyran -2- ketone compounds are as JMJD6 inhibitor and purposes. Patent. CN108218854 A.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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